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Rituximab: Mechanism, Applications, and Research Potential
Quick Facts About RituximabWhat is Rituximab?Rituximab is a monoclonal antibody targeting CD20, a protein found on the surface of B cells. It plays a crucial role in treating autoimmune diseases and certain cancers, such as non-Hodgkin's lymphoma.What is the mechanism of action for Rituximab?Rituximab works by binding to CD20, leading to B cell destruction through immune-mediated processes such as complement activation and apoptosis.What are the clinical applications of Rituximab?Rituximab is used to treat conditions like rheumatoid arthritis, chronic lymphocytic leukemia, and non-Hodgkin’s lymphoma. It’s also being explored for multiple sclerosis (MS) and lupus.What are the clinical applications of Rituximab?Rituximab is used to treat conditions like rheumatoid arthritis, ch
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12th Dec 2024
Tesnatilimab: Unveiling the Potential of Anti-CD47 in Cancer Research
Quick Facts About TesnatilimabWhat is Tesnatilimab?Tesnatilimab is an anti-CD47 monoclonal antibody designed to block the "don’t eat me" signal used by cancer cells to evade immune responses.What is the mechanism of action for Tesnatilimab?Tesnatilimab binds to the CD47 receptor on cancer cells, enhancing their phagocytosis by macrophages and other immune cells.What are the clinical applications of Tesnatilimab?It is being explored for its efficacy in treating various cancers, including hematologic malignancies and solid tumors.Is Tesnatilimab safe?Studies highlight its potential with a manageable safety profile, though some patients may experience mild-to-moderate immune-related side effects.1.) Understanding TesnatilimabTesnatilimab represents a cutting-edge advancement in
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10th Dec 2024