The YWHAZ Polyclonal Antibody (CAB7639) is a valuable tool for researchers studying the YWHAZ protein, also known as 14-3-3 zeta/delta. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it an excellent choice for Western blot applications. YWHAZ is a multifunctional protein involved in a variety of cellular processes, including signal transduction, cell cycle regulation, and apoptosis. Dysregulation of YWHAZ has been implicated in various diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases.
By using this antibody, researchers can detect and analyze YWHAZ expression in different cell types, allowing for a better understanding of its role in these pathologies.Studying YWHAZ and its interactions can provide valuable insights into disease mechanisms and potential therapeutic targets. The YWHAZ Polyclonal Antibody (CAB7639) is an essential tool for investigating the function of this protein in both normal and disease states, ultimately leading to advancements in biomedical research and drug development.
Product Name:
YWHAZ Rabbit Polyclonal Antibody
SKU:
CAB7639
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 146-245 of human YWHAZ (NP_003397.1).
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
7534
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using YWHAZ Rabbit pAb (CAB7639) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
