The XPO6 Polyclonal Antibody is a versatile tool for researchers studying the XPO6 protein, a key player in nucleocytoplasmic transport. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications. It binds to the XPO6 protein, enabling researchers to detect and analyze its expression in various cell types.XPO6 is involved in the transportation of proteins and RNA molecules between the nucleus and cytoplasm, making it essential for cellular functions such as gene expression and signal transduction. Dysregulation of XPO6 has been linked to various diseases, including cancer and neurodegenerative disorders.
Understanding the role of XPO6 in these contexts is vital for developing targeted therapies and improving patient outcomes.Whether investigating the basic biological functions of XPO6 or exploring its potential as a therapeutic target, the XPO6 Polyclonal Antibody offers reliable and accurate detection for a wide range of research applications. Explore the possibilities with this high-quality antibody and advance your studies in cell biology and disease mechanisms.
Product Name:
XPO6 Polyclonal Antibody
SKU:
CAB24463
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 116-216 of human XPO6 (NP_055986.1).
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
23214
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using XPO6 Rabbit pAb (CAB24463) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
