WNT5A Rabbit Monoclonal Antibody (CAB19133)
- SKU:
- CAB19133
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | WNT5A Rabbit Monoclonal Antibody |
SKU: | CAB19133 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 281-380 of human WNT5A (P41221). |
Sequence: | RGKL VQVN SRFN SPTT QDLV YIDP SPDY CVRN ESTG SLGT QGRL CNKT SEGM DGCE LMCC GRGY DQFK TVQT ERCH CKFH WCCY VKCK KCTE IVDQ FVCK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | hWNT5A; WNT5A |
Positive Sample: | HeLa,SK-OV-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7474 |
Clone Number: | ARC0405 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |