The WDR13 Antibody (PAC013226) is a polyclonal antibody designed for research involving WDR13, a protein involved in various cellular processes including transcriptional regulation and DNA repair. This antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in immunohistochemistry and immunofluorescence applications. It binds specifically to the WDR13 protein, enabling accurate detection and analysis in a variety of cell types.WDR13 is known to play a critical role in cell growth and differentiation, making it a potential target for research into cancer and developmental disorders.
Its function in DNA repair also suggests relevance in understanding genetic diseases and predicting responses to DNA-damaging therapies. By studying the activity of WDR13, researchers can gain insights into how this protein contributes to normal cellular function and disease progression, potentially leading to the development of novel therapeutic strategies.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]
