The VWA2 Antibody (PAC013212) is a polyclonal antibody designed for research involving the VWA2 protein, a cell surface molecule with roles in cell adhesion and extracellular matrix organization. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunohistochemistry.VWA2 is a key player in cell adhesion processes and is essential for maintaining tissue structure and integrity. Its involvement in extracellular matrix organization makes it an important target for research in developmental biology, tissue engineering, and cancer biology.
By detecting and analyzing the VWA2 protein in different cell types, this antibody enables researchers to explore its functions and potential therapeutic implications in various disease contexts.The VWA2 Antibody is a valuable tool for studying the role of VWA2 in cellular processes and disease mechanisms. Its specificity and reliability make it ideal for investigations into cell adhesion, tissue development, and cancer progression, providing valuable insights for the development of targeted therapies and treatment strategies.
von Willebrand factor A domain containing 2;VWA2;AMACO;CCSP-2;MGC157755 ;
UniProt Protein Function:
VWA2: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 10q25.3Cellular Component: extracellular space; basement membraneMolecular Function: identical protein bindingBiological Process: regulation of insulin receptor signaling pathway; calcium-independent cell-matrix adhesion; protein homooligomerization
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the von Willebrand factor A-like domain protein superfamily. The encoded protein is localized to the extracellular matrix and may serve as a structural component in basement membranes or in anchoring structures on scaffolds of collagen VII or fibrillin. This gene has been linked to type 1A diabetes and is a candidate serological marker for colon cancer. [provided by RefSeq, Jan 2013]
