The VSIG10 Polyclonal Antibody (PACO20860) is a valuable tool for researchers studying the VSIG10 protein, a member of the immunoglobulin superfamily implicated in immune regulation and cell adhesion. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in a variety of applications, including Western blot and immunohistochemistry.VSIG10 is known to play a role in immune response modulation, particularly in maintaining immune homeostasis and regulating inflammatory processes. Its involvement in cell adhesion suggests it may also have a role in tumor metastasis and tissue development.
Research into VSIG10 could provide insights into the mechanisms underlying diseases such as cancer, autoimmune disorders, and inflammatory conditions.By using the VSIG10 Polyclonal Antibody, researchers can accurately detect and analyze the presence of VSIG10 in various cell types, enabling a better understanding of its function and potential as a therapeutic target. This antibody is a valuable tool for studies in immunology, oncology, and cell biology, where the role of VSIG10 in immune regulation and disease pathogenesis is of interest.
Antibody Name:
VSIG10 Antibody (PACO20860)
Antibody SKU:
PACO20860
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human VSIG10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20860(VSIG10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20860(VSIG10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. The LOC147645 gene product has been provisionally designated LOC147645 pending further characterization.