The VNN1 Polyclonal Antibody (CAB3347) is a valuable tool for researchers studying the Vanin-1 protein, a key regulator of inflammation and oxidative stress. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot analysis.Vanin-1, also known as vascular non-inflammatory molecule 1, is involved in various physiological processes, including immune response modulation and lipid metabolism. Dysregulation of Vanin-1 has been linked to inflammatory diseases, metabolic disorders, and cancer, highlighting its importance in biomedical research.
By targeting the Vanin-1 protein, researchers can gain insights into its function and role in disease pathogenesis, paving the way for potential therapeutic interventions. The VNN1 Polyclonal Antibody is a reliable tool for investigating the complex mechanisms involving Vanin-1, making it a valuable asset for studies in immunology, metabolism, and cancer biology.
Product Name:
VNN1 Rabbit Polyclonal Antibody
SKU:
CAB3347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1 (NP_004657.2).
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Purification Method:
Affinity purification
Gene ID:
8876
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VNN1 Rabbit pAb (CAB3347) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
