The VEGFR3 (FLT-4) Polyclonal Antibody is a powerful tool for researchers studying the Vascular Endothelial Growth Factor Receptor 3 (VEGFR3), also known as FLT-4. This antibody, generated in rabbits, exhibits high specificity and reactivity towards VEGFR3 in human samples, making it an essential tool for Western blot applications.VEGFR3 is a key player in angiogenesis and lymphangiogenesis, making it a crucial target for studies in vascular biology and cancer research. This polyclonal antibody binds to the VEGFR3 protein, allowing for precise detection and analysis in various cell types.
Its versatility and effectiveness make it an ideal choice for researchers investigating the role of VEGFR3 in tumor progression, lymphatic vessel development, and other biological processes.By using the VEGFR3 (FLT-4) Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying angiogenesis and lymphangiogenesis, paving the way for the development of innovative therapeutic strategies for cancer and other diseases. Its reliability and specificity make it a valuable asset for cutting-edge research in the fields of oncology and vascular biology.
Product Name:
VEGFR3/Flt-4 Polyclonal Antibody
SKU:
CAB24866
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-229 of mouse VEGFR3/Flt-4(NP_032055.1).
Defects in FLT4 are the cause of lymphedema hereditary type 1A (LMPH1A) [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment._x000D_ Note=Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
Purification Method:
Affinity purification
Gene ID:
14257
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using VEGFR3/Flt-4 Rabbit pAb (CAB24866) at dilution of 1:50 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
