The UTP15 Polyclonal Antibody (PACO38838) is designed for research involving UTP15, a protein involved in RNA processing and metabolic pathways. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various experimental applications. It binds specifically to the UTP15 protein, allowing for detection and analysis in different cellular contexts, making it ideal for studies in molecular biology and genetic research.UTP15, also known as U3 small nucleolar RNA-associated protein 15, plays a crucial role in ribosome biogenesis and RNA processing, making it a key player in regulating gene expression.
Its involvement in essential cellular processes makes it a valuable target for research into diseases like cancer, developmental disorders, and genetic abnormalities. Understanding the function of UTP15 is essential for developing targeted therapies and interventions for these conditions.Overall, the UTP15 Polyclonal Antibody (PACO38838) offers a reliable tool for investigating the role of UTP15 in cellular processes and disease development, providing valuable insights for advancing scientific knowledge and potential therapeutic strategies.
Antibody Name:
UTP15 Antibody (PACO38838)
Antibody SKU:
PACO38838
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Recombinant Human U3 small nucleolar RNA-associated protein 15 homolog protein (234-518AA)
Western blot. All lanes: UTP15 antibody at 5µg/ml. Lane 1: Hela whole cell lysate. Lane 2: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 59, 37, 57 kDa. Observed band size: 59 kDa.
Background:
Involved in nucleolar processing of pre-18S ribosomal RNA.
Synonyms:
U3 small nucleolar RNA-associated protein 15 homolog, UTP15
UniProt Protein Function:
UTP15: Involved in nucleolar processing of pre-18S ribosomal RNA.Protein type: RNA-binding; RNA processing; NucleolusChromosomal Location of Human Ortholog: 5q13.2Cellular Component: small subunit processome; cytoplasm; nucleolus; cell junction; nucleusMolecular Function: snoRNA bindingBiological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); positive regulation of transcription from RNA polymerase I promoter
