The UNC79 Antibody (PAC047870) is a high-quality polyclonal antibody developed for research involving UNC79, a protein involved in ion channel activity and neurotransmitter release. Raised in rabbits, this antibody is highly specific for UNC79 in human samples and has been validated for use in various applications, including Western blotting and immunofluorescence.UNC79 is a key player in neuronal function, playing a crucial role in synaptic transmission and neuronal excitability. Its importance in ion channel regulation makes it a significant target for research in neuroscience and neurobiology.
By studying UNC79, researchers can gain valuable insights into the mechanisms underlying neuronal communication and potentially develop new therapeutic targets for neurological disorders.Overall, the UNC79 Antibody (PAC047870) is an essential tool for studying UNC79 expression and function in both normal and disease states, making it ideal for research in neuroscience, neurobiology, and related fields.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO47870 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO47870 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human brain tissue using PACO47870 at dilution of 1:100.
Background:
Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.
Synonyms:
Protein unc-79 homolog, UNC79, KIAA1409
UniProt Protein Function:
UNC79: Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability. Belongs to the unc-79 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ion channelChromosomal Location of Human Ortholog: 14q32.12Cellular Component: plasma membrane; integral to membraneBiological Process: multicellular organism growth; behavioral response to ethanol; transmembrane transport
