The UHRF1BP1 Polyclonal Antibody (PAC020826) is a valuable tool for research involving UHRF1BP1, a protein involved in epigenetic regulation and DNA repair processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the UHRF1BP1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cancer research.UHRF1BP1 is a crucial player in maintaining genomic stability and regulating gene expression through its interactions with various epigenetic modifiers. Its involvement in DNA repair mechanisms and chromatin organization highlights its significance in cancer development and progression.
By studying the function of UHRF1BP1, researchers can gain valuable insights into the molecular pathways involved in tumorigenesis and potentially identify new therapeutic targets for cancer treatment.In summary, the UHRF1BP1 Polyclonal Antibody is a reliable tool for investigating the role of UHRF1BP1 in epigenetic regulation and DNA repair processes. Its high specificity and sensitivity make it an essential component of research projects focused on understanding the molecular mechanisms underlying cancer biology and may lead to the development of novel therapeutic strategies for treating cancer.
Antibody Name:
UHRF1BP1 Antibody (PACO20826)
Antibody SKU:
PACO20826
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human UHRF1BP1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20826(UHRF1BP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20826(UHRF1BP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
UHRF1BP1 (UHRF1 binding protein 1) is a 1,440 amino acid, protein that interacts with UHRF1 and may act as a negative regulator of cell growth. The UHRF1BP1 protein has been identified as a possible risk loci for systemic lupus erythematosus. The UHRF1BP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish and C.elegans, and maps to human chromosome 6p21.31.
Synonyms:
UHRF1 binding protein 1
UniProt Protein Function:
UHRF1BP1: May act as a negative regulator of cell growth.Protein type: Unknown functionChromosomal Location of Human Ortholog: 6p21Molecular Function: histone deacetylase binding; identical protein binding; protein binding
