UGT2B7 Rabbit Polyclonal Antibody (CAB1693)
- SKU:
- CAB1693
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | UGT2B7 Rabbit Polyclonal Antibody |
SKU: | CAB1693 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-351 of human UGT2B7 (NP_001065.2). |
Sequence: | KVLV WAAE YSHW MNIK TILD ELIQ RGHE VTVL ASSA SILF DPNN SSAL KIEI YPTS LTKT ELEN FIMQ QIKR WSDL PKDT FWLY FSQV QEIM SIFG DITR KFCK DVVS NKKF MKKV QESR FDVI FADA IFPC SELL AELF NIPF VYSL SFSP GYTF EKHS GGFI FPPS YVPV VMSE LTDQ MTFM ERVK NMIY VLYF DFWF EIFD MKKW DQFY SEVL GRPT TLSE TMGK ADVW LIRN SWNF QFPY PLLP NVDF VGGL HCKP AKPL PKEM EDFV QSSG ENGV VVFS LGSM VSNM TEER ANVI ASAL AQIP QKVL WRFD GNKP DTLG LNT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 |
Synonyms: | UGT2B9; UDPGTH2; UDPGT2B7; UDPGTh-2; UDPGT 2B7; UDPGT 2B9; UGT2B7 |
Positive Sample: | HepG2,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | 70kDa |
The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7364 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |