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Tyrosine Hydroxylase Rabbit Monoclonal Antibody (CAB5079)

SKU:
CAB5079
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
DYT14
DYT5b
TYH
Research Area:
Metabolism
  • Metabolism Antibodies 3 Anti-Tyrosine Hydroxylase Antibody CAB5079
  • Metabolism Antibodies 3 Anti-Tyrosine Hydroxylase Antibody CAB5079
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Tyrosine Hydroxylase Rabbit Monoclonal Antibody
SKU:CAB5079
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Tyrosine Hydroxylase (P07101).
Sequence:MPTP DATT PQAK GFRR AVSE LDAK QAEA IMVR GQGA PGPS LTGS PWPG TAAP AASY TPTP RSPR FIGR RQSL IEDA RKER EAAV AAAA AAVP SEPG DPLE
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:TYH; DYT14; DYT5b; Tyrosine Hydroxylase
Positive Sample:SH-SY5Y,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:axon, cytoplasm, cytoplasmic side of plasma membrane, cytoplasmic vesicle, cytosol, dendrite, mitochondrion, neuron projection, nucleus, perikaryon, perinuclear region of cytoplasm, smooth endoplasmic reticulum, synaptic vesicle, terminal bouton
Calculated MW:59kDa
Observed MW:59kDa

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Purification Method:Affinity purification
Gene ID:7054
Clone Number:ARC1184
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Tyrosine Hydroxylase Rabbit mAb (CAB5079) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.

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