The TUBG2 Polyclonal Antibody (PAC041162) is specially designed for researchers studying TUBG2, a key protein involved in the regulation of microtubule dynamics and cell division. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding to the TUBG2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.TUBG2, also known as gamma-tubulin 2, plays a crucial role in nucleating microtubules and organizing the microtubule network within cells.
This function is essential for processes such as cell division, cell shape maintenance, and intracellular transport. The dysregulation of TUBG2 has been implicated in cancer development and progression, making it a promising target for therapeutic interventions.By investigating the function and regulation of TUBG2 using this polyclonal antibody, researchers can gain valuable insights into its role in cellular processes and disease mechanisms. This knowledge paves the way for the development of innovative treatments and therapies targeting TUBG2 for a variety of pathological conditions.
Immunohistochemistry of paraffin-embedded human breast cancer using PACO41162 at dilution of 1:100.
Western Blot. Positive WB detected in: Mouse skeletal muscle tissue. All lanes: TUBG2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa.
Background:
Tubulin is the major constituent of microtubules. The γ chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/β chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
