Anti-TUBA1C Antibody (PACO46302)

Antibody Name:	TUBA1C Antibody (PACO46302)
Antibody SKU:	PACO46302
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IP
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human Tubulin alpha-1C chain protein (29-184AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunohistochemistry of paraffin-embedded human prostate cancer using PACO46302 at dilution of 1:100.
	Immunoprecipitating TUBA1C in K562 whole cell lysate. Lane 1: Rabbit control IgG instead of PACO46302 in K562 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/50000). Lane 2: PACO46302 (4µg) + K562 whole cell lysate (500µg). Lane 3: K562 whole cell lysate (20µg).
	Western Blot. Positive WB detected in: K562 whole cell lysate, PC-3 whole cell lysate, U251 whole cell lysate, Mouse brain tissue. All lanes: TUBA1C antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa.

Background:	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain.
Synonyms:	Tubulin alpha-1C chain (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain], TUBA1C, TUBA6

UniProt Protein Function:	TUBA1C: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.Protein type: Cytoskeletal; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 12q13.12Cellular Component: microtubule; nucleus; vesicleMolecular Function: protein binding; structural molecule activityBiological Process: cell division; cytoskeleton-dependent intracellular transport; microtubule-based process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q9BQE3
NCBI GenInfo Identifier:	20455322
NCBI Gene ID:	84790
NCBI Accession:	Q9BQE3.1
UniProt Secondary Accession:	Q9BQE3
UniProt Related Accession:	Q9BQE3
Molecular Weight:	49,895 Da
NCBI Full Name:	Tubulin alpha-1C chain
NCBI Synonym Full Names:	tubulin alpha 1c
NCBI Official Symbol:	TUBA1C
NCBI Official Synonym Symbols:	TUBA6; bcm948
NCBI Protein Information:	tubulin alpha-1C chain
UniProt Protein Name:	Tubulin alpha-1C chain
UniProt Synonym Protein Names:	Alpha-tubulin 6; Tubulin alpha-6 chain
Protein Family:	Tubulin
UniProt Gene Name:	TUBA1C
UniProt Entry Name:	TBA1C_HUMAN

Antibodies

Secondary Antibody