The TRMT2A Polyclonal Antibody is a powerful tool for researchers studying TRMT2A, a key player in RNA modification and gene expression regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting TRMT2A in human samples, making it suitable for Western blotting applications. By binding to the TRMT2A protein, this antibody allows for precise analysis and visualization of TRMT2A in various cell types, facilitating in-depth investigations in fields such as molecular biology and cancer research.
TRMT2A, also known as tRNA methyltransferase 2 homolog A, is essential for maintaining proper tRNA function and protein synthesis. Dysregulation of TRMT2A has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular homeostasis. Research on TRMT2A can provide valuable insights into disease mechanisms and potential therapeutic targets, making this polyclonal antibody a valuable tool for advancing scientific understanding in these areas.
Product Name:
TRMT2A/HTF9C Polyclonal Antibody
SKU:
CAB21432
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2A/HTF9C (NP_073564.3).
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRMT2A/HTF9C Rabbit pAb (CAB21432) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
