TRIB2 Rabbit Polyclonal Antibody (CAB11661)
- SKU:
- CAB11661
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | TRIB2 Rabbit Polyclonal Antibody |
SKU: | CAB11661 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human TRIB2 (NP_067675.1). |
Sequence: | MNIH RSTP ITIA RYGR SRNK TQDF EELS SIRS AEPS QSFS PNLG SPSP PETP NLSH CVSC IGKY LLLE PLEG DHVF RAVH LHSG EELV CKVF DISC YQES LAPC FCLS AHSN INQI TEII |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | C5FW; TRB2; GS3955; TRIB2 |
Positive Sample: | K-562,293T,Raji,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytoskeleton. |
Calculated MW: | 39kDa |
Observed MW: | 49kDa |
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 28951 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |