TRAF3IP2 Rabbit Polyclonal Antibody (CAB6776)
- SKU:
- CAB6776
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | TRAF3IP2 Rabbit Polyclonal Antibody |
SKU: | CAB6776 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRAF3IP2 (NP_671733.2). |
Sequence: | MPPQ LQET RMNR SIPV EVDE SEPY PSQL LKPI PEYS PEEE SEPP APNI RNMA PNSL SAPT MLHN SSGD FSQA HSTL KLAN HQRP VSRQ VTCL RTQV LEDS EDSF CRRH PGLG KAFP SGCS AVSE PASE SVVG ALPA EHQF SFME KRNQ WLVS QLSA ASPD TGHD SDKS DQSL PNAS ADSL GGSQ EMVQ RPQP HRNR AGLD LPTI DTGY DSQP QDVL GIRQ LERP LPLT SVCY PQDL PRPL RSRE FPQF EPQR YPAC AQML PPNL SPHA PWNY HYHC PGSP DHQV PYGH DYPR AAYQ QVIQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; CANDF8; PSORS13; TRAF3IP2 |
Positive Sample: | Rat lung,Mouse lung,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasmic vesicle, nucleus |
Calculated MW: | 65kDa |
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Purification Method: | Affinity purification |
Gene ID: | 10758 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |