The TET3 Polyclonal Antibody (CAB18319) is a valuable tool for researchers studying TET3, a key enzyme involved in DNA demethylation and gene regulation. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the TET3 protein, allowing for easy detection and analysis in various cell types.TET3 plays a crucial role in epigenetic regulation and has been linked to various biological processes, including embryonic development, cell differentiation, and tumorigenesis. Its dysregulation has been implicated in diseases such as cancer, neurological disorders, and cardiovascular diseases.
Understanding the functions of TET3 can provide insights into these disease mechanisms and potentially lead to the development of targeted therapies.Researchers in the fields of epigenetics, cancer biology, and developmental biology will find the TET3 Polyclonal Antibody to be a valuable asset in their research endeavors. Its high specificity and sensitivity make it a reliable tool for studying the role of TET3 in various physiological and pathological processes.
Product Name:
TET3 Rabbit Polyclonal Antibody
SKU:
CAB18319
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 136-265 of TET3 (NP_001274420.1).
Enables methyl-CpG binding activity and zinc ion binding activity. Involved in histone H3-K4 trimethylation; positive regulation of transcription by RNA polymerase II; and protein O-linked glycosylation. Predicted to be located in cytoplasm and male pronucleus. Predicted to be active in nucleus. Biomarker of esophagus squamous cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
200424
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using TET3 Rabbit pAb (CAB18319) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
