The TBC1D14 Polyclonal Antibody (PAC042306) is a valuable tool for researchers studying TBC1D14, a protein involved in the regulation of cellular processes such as intracellular trafficking and autophagy. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.TBC1D14 is a key player in the regulation of membrane trafficking and autophagy, processes essential for maintaining cellular homeostasis and responding to stress. Dysregulation of TBC1D14 has been implicated in various diseases including cancer, neurodegenerative disorders, and metabolic syndromes, highlighting its potential as a therapeutic target.
By targeting TBC1D14 with this polyclonal antibody, researchers can effectively detect and analyze the protein in different cell types, enabling further investigations into its role in cellular processes and disease pathogenesis. This antibody is a valuable tool for studies in cell biology, molecular biology, and drug development, offering new insights into the functions of TBC1D14 and its potential as a target for therapeutic interventions.
Western blot. All lanes: TBC1D14 antibody at 4µg/ml. Lane 1: K562 whole cell lysate. Lane 2: U87 whole cell lysate. Lane 3: A549 whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 79, 48 kDa. Observed band size: 79 kDa.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42306 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO42306 at dilution of 1:100.
Background:
Negative regulator of starvation-induced autophagosome formation.
Synonyms:
TBC1 domain family member 14, TBC1D14, KIAA1322
UniProt Protein Function:
Negative regulator of starvation-induced autophagosome formation.