The TAS2R38 Polyclonal Antibody (CAB15087) is a valuable tool for researchers studying TAS2R38, a bitter taste receptor involved in determining individual differences in taste perception. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TAS2R38 protein, this antibody allows for the detection and analysis of TAS2R38 in various cell types, making it suitable for studies in taste perception and sensory science.TAS2R38 is a member of the TAS2R family of taste receptors, specifically responsible for detecting bitter tastes. Variations in the TAS2R38 gene have been linked to differences in bitter taste sensitivity, which can influence food preferences and dietary choices.
Understanding the role of TAS2R38 in taste perception is essential for research in areas such as nutrition, food science, and sensory perception.This TAS2R38 Polyclonal Antibody provides researchers with a reliable tool for investigating the function and expression of TAS2R38 in different experimental settings. By gaining insights into the genetic and molecular basis of taste perception, researchers can further explore the relationship between genetics, taste preferences, and overall food experiences.
Product Name:
TAS2R38 Rabbit Polyclonal Antibody
SKU:
CAB15087
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R38 (NP_789787.4).
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).
Purification Method:
Affinity purification
Gene ID:
5726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat thymus, using TAS2R38 Rabbit pAb (CAB15087) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
