The TARBP2 Polyclonal Antibody (CAB7533) is a valuable tool for researchers studying TARBP2, a protein involved in RNA processing and gene regulation. This antibody is raised in rabbits and has high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the TARBP2 protein, this antibody allows for its detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and gene expression.TARBP2, also known as trans-activation response RNA-binding protein 2, plays a crucial role in the processing of microRNAs and small interfering RNAs, which are important regulators of gene expression.
Dysregulation of TARBP2 has been implicated in diseases such as cancer and viral infections, making it a significant target for further research. Understanding the functions and mechanisms of TARBP2 is essential for developing potential therapies targeting gene regulation and RNA processing pathways. Overall, the TARBP2 Polyclonal Antibody (CAB7533) is a valuable tool for researchers interested in exploring the role of TARBP2 in various biological processes and disease states. Its high specificity and reactivity make it an excellent choice for studying the functions and regulation of TARBP2 in both normal and pathological conditions.
Product Name:
TARBP2 Rabbit Polyclonal Antibody
SKU:
CAB7533
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-366 of human TARBP2 (NP_599150.1).
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Purification Method:
Affinity purification
Gene ID:
6895
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TARBP2 Rabbit pAb (CAB7533) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
