tar Antibody (PACO34702)
- SKU:
- PACO34702
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
tar Antibody (PACO34702)
The TAR Polyclonal Antibody (PAC034702) is a valuable tool for research involving the TAR protein, a vital component in HIV-1 replication and transcription. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including Western blotting. By binding specifically to the TAR protein, this antibody enables accurate detection and analysis in diverse cell types, facilitating research in virology and infectious diseases.TAR, also known as trans-activating response element, plays a crucial role in the regulation of HIV-1 gene expression, making it a key target for antiviral drug development and understanding viral replication mechanisms.
Research on TAR is essential for developing novel therapies to combat HIV/AIDS and improve treatment outcomes. The TAR Polyclonal Antibody is a reliable tool for researchers exploring the molecular mechanisms of HIV-1 replication and identifying potential targets for antiviral interventions.
| Antibody Name: | tar Antibody (PACO34702) |
| Antibody SKU: | PACO34702 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Methyl-accepting chemotaxis protein II protein (212-553AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: tar antibody at 16µg/ml + DH5alpha whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 60 kDa. Observed band size: 60 kDa. |
| Background: | Receptor for the attractant L-aspartate and related amino and dicarboxylic acid,. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel. Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB. |
| Synonyms: | Methyl-accepting chemotaxis protein II (MCP-II) (Aspartate chemoreceptor protein), tar, cheM |
| UniProt Protein Function: | Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel. |
| UniProt Protein Details: | |
| NCBI Summary: | Tar senses maltose indirectly through periplasmic maltose binding protein. [More information is available at EcoGene: EG10988]. Tar is a chemoreceptor which senses aspartate and exists as a functional homodimer . [More information is available at EcoCyc: EG10988]. |
| UniProt Code: | P07017 |
| NCBI GenInfo Identifier: | 16129838 |
| NCBI Gene ID: | 946399 |
| NCBI Accession: | NP_416400.1 |
| UniProt Secondary Accession: | P07017,P76301 |
| UniProt Related Accession: | P07017 |
| Molecular Weight: | 52 kDa |
| NCBI Full Name: | methyl-accepting chemotaxis protein II |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | tar  |
| NCBI Official Synonym Symbols: | cheM; ECK1887; JW1875Â Â |
| NCBI Protein Information: | methyl-accepting chemotaxis protein II |
| UniProt Protein Name: | Methyl-accepting chemotaxis protein II |
| UniProt Synonym Protein Names: | Aspartate chemoreceptor protein |
| Protein Family: | Methyl-accepting chemotaxis protein |
| UniProt Gene Name: | tar  |
| UniProt Entry Name: | MCP2_ECOLI |
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