TAP1 Rabbit Polyclonal Antibody (CAB6213)
- SKU:
- CAB6213
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | TAP1 Rabbit Polyclonal Antibody |
SKU: | CAB6213 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 524-808 of human TAP1 (NP_000584.3). |
Sequence: | IYPR VQKA VGSS EKIF EYLD RTPR CPPS GLLT PLHL EGLV QFQD VSFA YPNR PDVL VLQG LTFT LRPG EVTA LVGP NGSG KSTV AALL QNLY QPTG GQLL LDGK PLPQ YEHR YLHR QVAA VGQE PQVF GRSL QENI AYGL TQKP TMEE ITAA AVKS GAHS FISG LPQG YDTE VDEA GSQL SGGQ RQAV ALAR ALIR KPCV LILD DATS ALDA NSQL QVEQ LLYE SPER YSRS VLLI TQHL SLVE QADH ILFL EGGA IREG GTHQ QLME KKGC YWAM VQAP ADAP E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | APT1; PSF1; ABC17; ABCB2; PSF-1; RING4; TAP1N; D6S114E; TAP1*0102N; TAP1 |
Positive Sample: | SKOV3,Jurkat,Mouse lung,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 81kDa |
Observed MW: | 68kDa |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6890 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |