The TAF3 Polyclonal Antibody (CAB17358) is a powerful tool for researchers studying TAF3, a key transcription factor essential for gene expression regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blot applications. By binding to the TAF3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for investigations in molecular biology and gene regulation studies.TAF3, also known as TBP-associated factor 3, plays a crucial role in the assembly of transcription pre-initiation complexes and is essential for proper gene transcription.
Its involvement in regulating gene expression makes it a significant target for research into various biological processes, including development, differentiation, and disease mechanisms. Understanding the functions of TAF3 is pivotal for unraveling the intricate pathways governing cellular processes and disease progression, paving the way for the development of targeted therapies and diagnostic tools.
Product Name:
TAF3 Rabbit Polyclonal Antibody
SKU:
CAB17358
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TAF3 (NP_114129.1).
male germ cell nucleus, nuclear membrane, nucleoplasm, nucleus
Calculated MW:
104kDa
Observed MW:
80kDa/140kDa
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).
Purification Method:
Affinity purification
Gene ID:
83860
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TAF3 Rabbit pAb (CAB17358) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
