The SUMO4 Polyclonal Antibody (CAB3100) is a valuable tool for researchers studying SUMO4, a small ubiquitin-like modifier protein that plays a key role in regulating cellular processes such as protein localization, stability, and activity. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting SUMO4 in human samples, making it an ideal choice for Western blotting applications.SUMO4 is known to be involved in various biological pathways, including DNA repair, transcriptional regulation, and cell cycle progression. Dysregulation of SUMO4 has been implicated in the development of certain diseases, such as cancer and neurodegenerative disorders.
By using the SUMO4 Polyclonal Antibody, researchers can gain insights into the function and regulation of SUMO4 in different cell types, paving the way for potential therapeutic strategies targeting SUMOylation pathways.Overall, the SUMO4 Polyclonal Antibody (CAB3100) offers researchers a reliable tool for studying the role of SUMO4 in cellular processes and disease pathogenesis, ultimately contributing to advancements in the field of molecular biology and drug development.
Product Name:
SUMO4 Rabbit Polyclonal Antibody
SKU:
CAB3100
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-95 of human SUMO4 (Q6EEV6).
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
Purification Method:
Affinity purification
Gene ID:
387082
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SUMO4 Rabbit pAb (CAB3100) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
