STARD4 Rabbit Polyclonal Antibody (CAB15955)
- SKU:
- CAB15955
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | STARD4 Rabbit Polyclonal Antibody |
SKU: | CAB15955 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1). |
Sequence: | MEGL SDVA SFAT KLKN TLIQ YHSI EEDK WRVA KKTK DVTV WRKP SEEF NGYL YKAQ GVID DLVY SIID HIRP GPCR LDWD SLMT SLDI LENF EENC CVMR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | STARD4 |
Positive Sample: | Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytoplasmic vesicle, cytosol, endoplasmic reticulum |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Purification Method: | Affinity purification |
Gene ID: | 134429 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |