The Sorting Nexin 3 Polyclonal Antibody (CAB7502) is a valuable tool for researchers studying the Sorting Nexin 3 protein, which plays a crucial role in intracellular protein trafficking and sorting. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.Sorting Nexin 3 is involved in the regulation of endosomal sorting and vesicle trafficking pathways, making it a key player in various cellular processes such as receptor recycling and degradation. By targeting the Sorting Nexin 3 protein, researchers can gain insights into the mechanisms underlying these processes and their impact on cell function.
This antibody is ideal for researchers in the fields of cell biology, molecular biology, and biochemistry who are interested in studying intracellular trafficking pathways and the role of Sorting Nexin 3 in cellular physiology. By utilizing this antibody in their experiments, researchers can further our understanding of these complex processes and potentially uncover new therapeutic targets for a range of diseases related to defects in protein sorting and trafficking.
Product Name:
SNX3 Rabbit Polyclonal Antibody
SKU:
CAB7502
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-162 of human SNX3 (NP_003786.1).
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
8724
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SNX3 antibody (CAB7502) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
