The SLC6A7 Antibody (PAC031816) is a valuable tool for researchers studying SLC6A7, a solute carrier protein involved in neurotransmitter uptake. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SLC6A7 protein, this antibody enables researchers to detect and analyze the expression of SLC6A7 in various cell types, making it an essential component in studies related to neuroscience, neuropharmacology, and psychiatric disorders.SLC6A7, also known as the taurine transporter, plays a crucial role in the regulation of taurine levels in the brain and other tissues. Taurine is an important neurotransmitter and antioxidant, with implications for various neurological processes, including neuronal development, neurotransmission, and neuroprotection.
Dysregulation of taurine levels has been linked to conditions such as epilepsy, neurodegenerative diseases, and mood disorders, highlighting the significance of SLC6A7 as a potential therapeutic target.By utilizing the SLC6A7 Antibody (PAC031816), researchers can gain insights into the function and regulation of SLC6A7 in health and disease, paving the way for the development of novel therapeutic strategies targeting taurine transport and metabolism. This antibody is a valuable tool for advancing our understanding of taurine biology and its implications for neurological and psychiatric
Antibody Name:
SLC6A7 Antibody (PACO31816)
Antibody SKU:
PACO31816
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Sodium-dependent proline transporter protein (557-636AA)
Immunohistochemistry of paraffin-embedded human brain tissue using PACO31816 at dilution of 1:100.
Background:
Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.
Synonyms:
Sodium-dependent proline transporter (Solute carrier family 6 member 7), SLC6A7, PROT
UniProt Protein Function:
Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.
UniProt Protein Details:
NCBI Summary:
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
