The SLC25A20 Polyclonal Antibody (CAB13956) is specifically designed for research involving SLC25A20, a mitochondrial carnitine/acylcarnitine translocase involved in fatty acid metabolism. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC25A20 protein, this antibody enables accurate detection and analysis in various cell types, making it a valuable tool for studies in metabolism and energy regulation.SLC25A20, also known as carnitine-acylcarnitine translocase, plays a crucial role in transporting fatty acids into mitochondria for beta-oxidation, a key process in energy production.
Its involvement in fatty acid metabolism highlights its importance in diseases related to mitochondrial dysfunction and metabolic disorders. Research on SLC25A20 can provide insights into the underlying mechanisms of these conditions and aid in the development of potential therapies targeting fatty acid metabolism.Overall, the SLC25A20 Polyclonal Antibody (CAB13956) is a reliable tool for researchers investigating the role of SLC25A20 in metabolic pathways and related diseases. Its specificity and sensitivity make it an essential component in studies aiming to unravel the complexities of fatty acid metabolism and mitochondrial function.
Product Name:
SLC25A20 Rabbit Polyclonal Antibody
SKU:
CAB13956
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC25A20 (NP_000378.1).
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Purification Method:
Affinity purification
Gene ID:
788
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC25A20 Rabbit pAb (CAB13956) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
