The SLC18A2 Polyclonal Antibody (CAB2799) is a valuable tool for researchers studying SLC18A2, a vesicular monoamine transporter involved in neurotransmitter transport and storage. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By specifically targeting the SLC18A2 protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for studies in neurobiology and psychiatric research.SLC18A2 plays a crucial role in regulating the release of neurotransmitters such as serotonin, dopamine, and norepinephrine in the central nervous system. Dysregulation of SLC18A2 has been linked to various neurological disorders, including depression, schizophrenia, and Parkinson's disease.
By understanding the function of SLC18A2, researchers can gain insights into the pathophysiology of these conditions and potentially develop novel therapeutic approaches targeting SLC18A2.Overall, the SLC18A2 Polyclonal Antibody (CAB2799) is a valuable research tool for investigating the role of SLC18A2 in neurotransmission and its implications for neurological disorders. Its high specificity and sensitivity make it a reliable choice for researchers looking to advance our understanding of the neurobiology of neurotransmitter transport and storage.
Product Name:
SLC18A2 Rabbit Polyclonal Antibody
SKU:
CAB2799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 50-130 of human SLC18A2 (NP_003045.2).
This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments.
Purification Method:
Affinity purification
Gene ID:
6571
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC18A2 Rabbit pAb (CAB2799) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
