The SLC12A2 Polyclonal Antibody (CAB11675) is specifically designed for research involving the SLC12A2 protein, also known as sodium-potassium-chloride cotransporter 2. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds to the SLC12A2 protein, enabling accurate detection and analysis in various cell types, making it an excellent tool for studies in physiology, neuroscience, and kidney function research.The SLC12A2 protein plays a critical role in ion transport and fluid balance in the body, particularly in the kidney and brain.
Dysregulation of SLC12A2 has been implicated in various diseases, including hypertension, epilepsy, and kidney disorders. Understanding the function and expression of SLC12A2 is crucial for advancing our knowledge of these conditions and developing targeted therapies.Researchers interested in studying the role of SLC12A2 in human health and disease will benefit from using the SLC12A2 Polyclonal Antibody (CAB11675) as a reliable tool for their experiments. Its high reactivity and specificity make it a valuable asset for investigating the physiological and pathophysiological functions of the SLC12A2 protein.
Product Name:
SLC12A2 Rabbit Polyclonal Antibody
SKU:
CAB11675
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human SLC12A2 (NP_001037.1).
The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC12A2 antibody (CAB11675) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
