SLC10A2 Rabbit Polyclonal Antibody (CAB12846)
- SKU:
- CAB12846
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SLC10A2 Rabbit Polyclonal Antibody |
SKU: | CAB12846 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 289-348 of human SLC10A2 (NP_000443.1). |
Sequence: | FPLI YSIF QLAF AAIF LGFY VAYK KCHG KNKA EIPE SKEN GTEP ESSF YKAN GGFQ PDEK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ASBT; IBAT; ISBT; PBAM; NTCP2; PBAM1; SLC10A2 |
Positive Sample: | HT-29,Mouse small intestine,Mouse kidney,Rat small intestine,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
Purification Method: | Affinity purification |
Gene ID: | 6555 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |