The SGcz Polyclonal Antibody (CAB15958) is a vital tool for researchers studying SGcz, a protein involved in cellular processes and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to SGcz, researchers can accurately detect and analyze the protein in various cell types, making it an essential component for studies in cell biology and signal transduction.SGcz, also known as Signal-Regulated Protein, plays a crucial role in regulating cellular function and response to external stimuli.
Its involvement in signaling cascades and cellular communication makes it a target of interest for research into developmental biology, cancer, and neurodegenerative diseases. Understanding the function of SGcz is essential for unraveling its role in disease pathology and potential therapeutic interventions.Overall, the SGcz Polyclonal Antibody (CAB15958) provides researchers with a reliable tool for investigating the function and regulation of SGcz in diverse biological contexts, ultimately contributing to advancements in our understanding of cellular processes and disease mechanisms.
Product Name:
SGCZ Rabbit Polyclonal Antibody
SKU:
CAB15958
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 83-312 of human SGCZ (NP_631906.2).
Cell membrane, Cytoplasm, Single-pass type II membrane protein, cytoskeleton, sarcolemma.
Calculated MW:
33kDa
Observed MW:
38kDa
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
Purification Method:
Affinity purification
Gene ID:
137868
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SGCZ Rabbit pAb (CAB15958) at 1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
