The Selenot Antibody (PACO34586) is a polyclonal antibody designed for research involving Selenot, a protein that plays a crucial role in antioxidant defense and redox regulation. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.Selenot is a key player in maintaining cellular homeostasis and protecting cells from oxidative damage. It is involved in regulating the levels of reactive oxygen species (ROS) and is essential for the proper function of enzymes involved in antioxidant defense.
Research into Selenot is important for understanding its role in oxidative stress-related diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases.By using the Selenot Antibody, researchers can detect and analyze the expression of Selenot in different cell types and tissues, allowing for a deeper understanding of its function in health and disease. This antibody is a valuable tool for studies in biochemistry, molecular biology, and pharmacology, providing insight into the mechanisms underlying oxidative stress and the potential for therapeutic interventions targeting Selenot.
Antibody Name:
Selenot Antibody (PACO34586)
Antibody SKU:
PACO34586
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Thioredoxin reductase-like selenoprotein T protein (20-195AA)
Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9), Selenot, Selt
UniProt Protein Function:
SELT: a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]Protein type: Secreted, signal peptide; SecretedCellular Component: endoplasmic reticulumBiological Process: glucose homeostasis; pancreas development; response to glucose stimulus
UniProt Protein Details:
NCBI Summary:
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
