SARS Nucleocapsid HRP Monoclonal Antibody [PT3851] (CPAB0423)
- SKU:
- CPAB0423
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Virus
- Clone:
- PT3851
- Applications:
- ELISA
Description
SARS Nucleocapsid HRP Monoclonal Antibody [PT3851] (CPAB0423)
The SARS Nucleocapsid HRP Antibody (CPAB0423) is a crucial tool for researchers studying the SARS virus and its interactions with host cells. This antibody, produced in rabbits, specifically binds to the nucleocapsid protein of the SARS virus, allowing for accurate detection and analysis in various experimental settings.The SARS nucleocapsid protein plays a key role in viral replication and assembly, making it a valuable target for antiviral drug development and vaccine research.
By using this antibody in techniques such as Western blotting, researchers can gain valuable insights into the behavior of the SARS virus and potential therapeutic targets.With its high reactivity in human samples and validation for use in various applications, the SARS Nucleocapsid HRP Antibody (CPAB0423) is an essential tool for advancing our understanding of the SARS virus and developing effective strategies to combat its spread.
Product Name: | SARS Nucleocapsid HRP Antibody |
Product Sku: | CPAB0423 |
Size: | 100μg |
Host Species: | |
Immunogen: | Recombinant protein fragment 1-49 a.aof the SARS nucleoprotein. |
Clone: | PT3851 |
Reactivity: | Viral |
Applications: | ELISA |
Purification Method: | Protein A affinity purified. |
Isotype: | |
Background: | SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. |
Synonyms: | |
Storage Buffer: |