SAG Rabbit Polyclonal Antibody (CAB13045)
- SKU:
- CAB13045
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Description
Product Name: | SAG Rabbit Polyclonal Antibody |
SKU: | CAB13045 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human SAG (NP_000532.2). |
Sequence: | MAAS GKTS KSEP NHVI FKKI SRDK SVTI YLGN RDYI DHVS QVQP VDGV VLVD PDLV KGKK VYVT LTCA FRYG QEDI DVIG LTFR RDLY FSRV QVYP PVGA ASTP TKLQ ESLL KKLG SNTY PFLL TFPD YLPC SVML QPAP QDSG KSCG VDFE VKAF ATDS TDAE EDKI PKKS SVRL LIRK VQHA PLEM GPQP RAEA AWQF FMSD KPLH LAVS LNKE IYFH GEPI PVTV TVTN NTEK TVKK IKAF VEQV ANVV LYSS DYYV KPVA MEEA QEKV PPNS TLTK TLTL LPLL ANNR ERRG IALD GKIK HEDT NLAS STII KEGI DRTV LGIL VSYQ IKVK LTVS GFLG ELTS SEVA TEVP FRLM HPQP EDPA KESY QDAN LVFE EFAR HNLK DAGE AEEG KRDK NDVD E |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | RP47; RP96; S-AG; SAG |
Positive Sample: | Mouse eye,Rat eye |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, photoreceptor inner segment, photoreceptor outer segment |
Calculated MW: | 45kDa |
Observed MW: | 52kDa |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness.
Purification Method: | Affinity purification |
Gene ID: | 6295 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |