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RUNX1 Polyclonal Antibody (CAB24747)

SKU:
CAB24747
€259
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RUNX1 Polyclonal Antibody
SKU:CAB24747
Size:100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RUNX1.
Tested Applications:WB
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; CBF2alpha; AML1-EVI-1; PEBP2alpha; RUNX1
Positive Sample:Jurkat,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:49kDa
Observed MW:55kDa

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:861
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using RUNX1 Rabbit pAb (CAB24747) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): SH-SY5Y.Exposure time: 60s.

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