S6 Ribosomal Protein (RPS6) Rabbit Polyclonal Antibody (CAB6058)
- SKU:
- CAB6058
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | S6 Ribosomal Protein (RPS6) Rabbit Polyclonal Antibody |
SKU: | CAB6058 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-130 of human RPS6 (NP_001001.2). |
Sequence: | MKLN ISFP ATGC QKLI EVDD ERKL RTFY EKRM ATEV AADA LGEE WKGY VVRI SGGN DKQG FPMK QGVL THGR VRLL LSKG HSCY RPRR TGER KRKS VRGC IVDA NLSV LNLV IVKK GEKD IPGL TDTT VP |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | S6; eS6; S6 Ribosomal Protein (RPS6) |
Positive Sample: | SKOV3,Raji,HT-29,A-431,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytoplasmic ribonucleoprotein granule, cytosol, cytosolic ribosome, endoplasmic reticulum, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm |
Calculated MW: | 29kDa |
Observed MW: | 32kDa |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Purification Method: | Affinity purification |
Gene ID: | 6194 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |