The RPL36A Polyclonal Antibody (CAB15717) is a valuable tool for researchers studying RPL36A, a ribosomal protein involved in protein synthesis. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RPL36A protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetics.RPL36A is a key component of the ribosome, the cellular machinery responsible for translating genetic information into proteins. Its role in protein synthesis makes it essential for cell growth and function, with dysregulation of RPL36A protein expression linked to various diseases, including cancer and genetic disorders.
Research on RPL36A can provide insights into fundamental cellular processes and potential therapeutic targets for these conditions.By using the RPL36A Polyclonal Antibody (CAB15717), researchers can delve deeper into the functions and regulation of RPL36A, advancing our understanding of protein synthesis and its implications for health and disease. This antibody is a valuable resource for scientists investigating ribosomal biology, gene expression, and related fields in both basic and applied research.
Product Name:
RPL36A Rabbit Polyclonal Antibody
SKU:
CAB15717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-142 of human RPL36A (NP_066357.2).
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene.
Purification Method:
Affinity purification
Gene ID:
6173
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using RPL36A Rabbit pAb (CAB15717) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
