The RNASEH2C Polyclonal Antibody (CAB13884) is a valuable tool for researchers studying RNASEH2C, a protein involved in DNA replication and repair processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By binding to the RNASEH2C protein, this antibody enables accurate detection and analysis of RNASEH2C expression in a variety of cell types.RNASEH2C plays a crucial role in maintaining genomic stability by removing RNA primers during DNA replication. Dysregulation of RNASEH2C has been linked to various human diseases, including Aicardi-Goutières Syndrome and systemic lupus erythematosus.
Therefore, the study of RNASEH2C is essential for understanding the molecular processes underlying these conditions and developing targeted therapies.With its high reactivity and specificity, the RNASEH2C Polyclonal Antibody (CAB13884) is a valuable tool for researchers investigating the functions and dysregulation of RNASEH2C in both normal cellular processes and disease states. Its application in Western blot analyses provides reliable and accurate results, making it a versatile tool for studies in molecular biology, genetics, and disease research.
Product Name:
RNASEH2C Rabbit Polyclonal Antibody
SKU:
CAB13884
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human RNASEH2C (NP_115569.2).
This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.
Purification Method:
Affinity purification
Gene ID:
84153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RNASEH2C Rabbit pAb (CAB13884) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
