The RhoA/C Antibody (PAC061358) is a polyclonal antibody specifically designed for research purposes involving RhoA and RhoC proteins, key regulators of cytoskeletal dynamics and cell migration. This antibody is raised in rabbits and has been validated for use in Western blot applications. It binds to RhoA and RhoC proteins, allowing for accurate detection and analysis in various cell types, making it an essential tool for studies in cell biology, cancer research, and drug development.RhoA and RhoC proteins are crucial for cell morphology, adhesion, and migration, playing significant roles in cancer metastasis and invasion.
The dysregulation of these proteins is associated with various diseases, including cancer and neurological disorders. Therefore, understanding the function and activity of RhoA and RhoC is essential for developing targeted therapies and strategies to inhibit their aberrant signaling pathways.The RhoA/C Antibody (PAC061358) provides researchers with a reliable tool to investigate the role of RhoA and RhoC proteins in cellular processes and disease progression, offering valuable insights into potential therapeutic targets and treatment options.
Antibody Name:
rhoac Antibody (PACO61358)
Antibody SKU:
PACO61358
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Zebrafish
Immunogen:
Recombinant Zebrafish Rho-related GTP-binding protein RhoA-C protein (1-190AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: rhoac antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 51 kDa. Observed band size: 56 kDa.
Background:
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
Synonyms:
Rho-related GTP-binding protein RhoA-C, rhoac
UniProt Protein Function:
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
