Human EphA3 Recombinant Protein (RPES1516)
- SKU:
- RPES1516
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
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Human EphA3 Recombinant Protein
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
| Product Name: | Human EphA3 Recombinant Protein (RPES1516) |
| Product Code: | RPES1516 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | EK4,ETK,ETK1,HEK,HEK4,TYRO4 |
| Accession: | NP_005224.2 |
| Sequence: | Met 1-Gln541 |
| Fusion tag: | C-His |
| Activity: | Measured by its binding ability in a functional ELISA.Immobilized human EPHA3-His at 10 µg/ml (100 ?l/well) can bind human EphrinA5-Fc , The EC50 of human EphrinA5-Fc is 6.2-14.6 ng/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human EPHA3 (Met1-Gln541) was expressed with a polyhistidine tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 60.3 kDa |
| AP Mol Mass: | 65-70 kDa |
| Formulation: | Lyophilized from sterile PBS, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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