The RCN1 Polyclonal Antibody is a highly specific research tool designed for scientists studying RCN1, a protein involved in various cellular functions. This antibody, produced in rabbits, has been validated for use in Western blot applications and is especially reactive with human samples. By binding to the RCN1 protein, researchers can efficiently detect and analyze RCN1 expression in different cell types.RCN1, also known as Reticulocalbin-1, plays a crucial role in calcium homeostasis and protein folding within the endoplasmic reticulum.
Dysregulation of RCN1 has been associated with diseases such as cancer, neurodegenerative disorders, and diabetes. As such, investigating the function of RCN1 using this antibody may provide valuable insights into the molecular mechanisms underlying these conditions.Overall, the RCN1 Polyclonal Antibody is an essential tool for researchers seeking to explore the role of RCN1 in various physiological and pathological processes, ultimately contributing to the development of novel therapeutic interventions and diagnostic strategies.
Product Name:
RCN1 Polyclonal Antibody
SKU:
CAB21590
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-331 of human RCN1 (NP_002892.1).
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
Purification Method:
Affinity purification
Gene ID:
5954
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RCN1 Rabbit pAb (CAB21590) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
