The RBMS3 Polyclonal Antibody (CAB17142) is a valuable tool for researchers studying RBMS3, a RNA-binding protein involved in various cellular processes such as RNA metabolism, splicing, and transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RBMS3 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an ideal choice for investigations in molecular biology and cancer research.RBMS3, also known as RNA-binding protein with multiple splicing 3, plays a crucial role in the regulation of gene expression and alternative splicing, making it a key player in the control of cell growth, differentiation, and proliferation.
Dysregulation of RBMS3 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. Therefore, elucidating the functions of RBMS3 is essential for gaining insights into disease mechanisms and developing targeted therapeutics. Overall, the RBMS3 Polyclonal Antibody (CAB17142) offers researchers a reliable tool for studying the biological functions and mechanisms of RBMS3, paving the way for advancements in biomedical research and potential therapeutic interventions.
Product Name:
RBMS3 Rabbit Polyclonal Antibody
SKU:
CAB17142
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 334-433 of human RBMS3 (NP_001171183.1).
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBMS3 Rabbit pAb (CAB17142) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
