The RB Monoclonal Antibody is a powerful tool for researchers studying CD300A, a crucial cell surface molecule involved in immune regulation. This antibody, derived from rabbit B cells, is specifically designed for use in Western blot applications and is highly reactive with human samples. By binding to the CD300A protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a key role in maintaining immune balance by regulating inflammation and suppressing allergic reactions.
Its importance in modulating immune responses makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is essential for the development of new therapies that can either augment or suppress immune responses in these disease contexts. Overall, the RB Monoclonal Antibody offers researchers a reliable and effective tool for investigating the role of CD300A in immune regulation, providing valuable insights for the development of targeted therapies in various disease settings.
Product Name:
RB Monoclonal Antibody
SKU:
CAB22663
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 750-850 of human RB1 (NP_000312.2).
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Purification Method:
Affinity purification
Gene ID:
5925
Clone Number:
ARC57809
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using RB Rabbit mAb (CAB22663) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.