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RASGEF1B Antibody (PACO35246)

SKU:
PACO35246
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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RASGEF1B Antibody (PACO35246)

The RasGEF1B Polyclonal Antibody (PACO35246) is a powerful tool for researchers studying RasGEF1B, a protein involved in cell signaling pathways and regulation of cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting RasGEF1B in human samples, making it suitable for use in Western blotting and immunohistochemistry applications.RasGEF1B is a guanine nucleotide exchange factor that activates the small GTPase Ras, playing a key role in signal transduction and cellular growth control.

Dysregulation of RasGEF1B has been linked to various diseases, including cancer and neurological disorders, making it a promising therapeutic target. By utilizing the RasGEF1B Polyclonal Antibody, researchers can investigate the expression levels and localization of RasGEF1B in different cell types and tissues, providing valuable insights into its function and potential implications in disease pathology.

Antibody Name:RASGEF1B Antibody (PACO35246)
Antibody SKU:PACO35246
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Ras-GEF domain-containing family member 1B protein (1-300AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry of paraffin-embedded human small intestine tissue using PACO35246 at dilution of 1:100.
Background:Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Synonyms:Ras-GEF domain-containing family member 1B (GPI gamma-4), RASGEF1B, GPIG4
UniProt Protein Function:Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q0VAM2
NCBI GenInfo Identifier:663429556
NCBI Gene ID:153020
NCBI Accession:NP_001287664.1
UniProt Secondary Accession:Q0VAM2,Q0VAM1, Q4W5L7, Q4W5M3, Q96MY8
UniProt Related Accession:Q0VAM2
Molecular Weight:52
NCBI Full Name:ras-GEF domain-containing family member 1B isoform 2
NCBI Synonym Full Names:RasGEF domain family member 1B
NCBI Official Symbol:RASGEF1B  
NCBI Official Synonym Symbols:GPIG4  
NCBI Protein Information:ras-GEF domain-containing family member 1B
UniProt Protein Name:Ras-GEF domain-containing family member 1B
UniProt Synonym Protein Names:GPI gamma-4
Protein Family:
UniProt Gene Name:RASGEF1B  
UniProt Entry Name:
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