The Rab40B Polyclonal Antibody (PACO11662) is a valuable tool for researchers studying Rab40B, a protein involved in intracellular trafficking and vesicle transport. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting Rab40B in various biological samples, particularly in Western blot experiments.Rab40B is a member of the Rab GTPase family that plays a crucial role in regulating membrane trafficking processes within cells. Its functions include modulating vesicle formation and transport, as well as controlling the dynamics of intracellular organelles.
By targeting Rab40B with this antibody, researchers can investigate its involvement in cellular pathways related to protein sorting, secretion, and signaling.The significance of Rab40B in cellular physiology and disease makes it an attractive target for research in areas such as cancer, neurodegeneration, and infectious diseases. Studying the regulation and function of Rab40B using this antibody can provide valuable insights into the mechanisms underlying these pathologies, ultimately contributing to the development of novel therapeutic strategies.
RAB40B, member RAS oncogene family;RAB40B;FLJ42385;RAR;SEC4L ;
UniProt Protein Function:
RAB40B: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein; G protein, monomeric; G protein, monomeric, RabChromosomal Location of Human Ortholog: 17q25.3Cellular Component: plasma membrane; endosome membraneMolecular Function: GTPase activity; GDP binding; GTP bindingBiological Process: regulation of exocytosis; intracellular protein transport; protein secretion; protein ubiquitination; Rab protein signal transduction; vesicle docking during exocytosis
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008]
