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Purified Anti-Human CD41 Antibody [HIP8] (AGEL3507)

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SKU AGEL3507
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone HIP8
Conjugation Unconjugated
€25 - €63
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Description

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Purified Anti-Human CD41 Antibody [HIP8]

The Purified Anti-Human CD41 Antibody (HIP8) is a high-quality research tool specifically designed for studies involving the CD41 antigen, also known as integrin alpha IIb. This antibody is raised and purified against human samples, ensuring high sensitivity and specificity in experimental applications.CD41 is a cell surface protein primarily expressed on platelets and megakaryocytes, playing a crucial role in platelet aggregation and hemostasis. The Purified Anti-Human CD41 Antibody (HIP8) is validated for use in various research techniques such as flow cytometry, immunofluorescence, and immunohistochemistry. By binding specifically to CD41, this antibody enables precise detection and analysis of the protein in different cellular contexts.

Investigations into CD41 are essential for understanding platelet biology, thrombosis, and hemostasis, making this antibody a valuable asset for researchers focusing on cardiovascular diseases, hematological disorders, and coagulation processes. Its reliability and specificity make it an ideal tool for exploring the functions of CD41 and its implications in health and disease.In summary, the Purified Anti-Human CD41 Antibody (HIP8) offers researchers a versatile and effective means to study the CD41 antigen in various experimental settings, facilitating advancements in the fields of hematology, cardiovascular research, and thrombosis-related studies.

Product Title:Purified Anti-Human CD41 Antibody [HIP8]
SKU:AGEL3507
Size:25µg, 100µg
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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